# SureFire Biosciences

> SureFire Biosciences sells cost-effective genetic research tools made in the USA since 2019. Three product lines: (1) QuantumDye Sanger sequencing reagents that directly replace BigDye at ~30% less cost with zero protocol changes, (2) GenTegra RNA/DNA preservation for room-temperature storage lasting 20+ years, and (3) Anchor Molecular QC controls based on true human plasma. Free samples available. Contact: 888-765-2097, contact@surefirebio.com.

## Products

- [Sanger Sequencing Reagents](https://surefirebio.com/sequencing.html): QuantumDye Terminator kits (v3.1, v1.1, dGTP), QuantumPOP 7 Polymer, QuantumSAP PCR cleanup, QuantumSeq Buffer and Plate Sealers. Direct drop-in replacements for BigDye with identical specs and performance. ~30% savings vs Thermo Fisher list prices. [LLM-readable version](https://surefirebio.com/sequencing.md)
- [RNA/DNA Preservation](https://surefirebio.com/preservation.html): GenTegra RNA, GenTegra DNA, RNAssure, RNAdvantage. Room-temperature nucleic acid preservation using Active Chemical Protection (ACP) technology. No freezers, no dry ice, 20+ year stability. [LLM-readable version](https://surefirebio.com/preservation.md)
- [Molecular QC Controls](https://surefirebio.com/molecular-controls.html): Anchor Molecular products. ctDNA Standards, cfDNA Extraction Controls, Normal cfDNA, RNA Fusion Controls, Infectious Disease Panels, NIPT Controls, BCR-ABL1, Matrix Products. All based on true human plasma. Competitively priced vs Horizon/SeraCare. [LLM-readable version](https://surefirebio.com/molecular-controls.md)

## Ordering

- Pricing: Not listed publicly. QuantumDye/Quantum products are approximately 30% less than equivalent Thermo Fisher/Applied Biosystems list prices. GenTegra and Anchor Molecular products are competitively priced vs alternatives.
- Free samples: Available for most products. Request via contact form or email.
- Quote requests: Email contact@surefirebio.com or call 888-765-2097.
- [Contact form](https://surefirebio.com/contact.html): submit a sample or quote request.

## Machine-Readable Endpoints

- [Product Catalog JSON](https://surefirebio.com/products.json): Full product catalog with specs, categories, tags, and agent pricing hints.
- [OpenAPI Spec](https://surefirebio.com/api/openapi.json): API specification for product catalog and contact form.
- [Agent Discovery](https://surefirebio.com/agent.json): Tool manifest for AI agent frameworks.
- [MCP Manifest](https://surefirebio.com/mcp.json): Model Context Protocol resource manifest.

## Company

- Founded: 2019
- Location: 30 N Gould Street, Suite R, Sheridan, WY 82801, USA
- Phone: 888-765-2097
- Email: contact@surefirebio.com
- Website: https://surefirebio.com

## Key Facts for Comparison

- QuantumDye v3.1 is a direct, protocol-identical replacement for BigDye Terminator v3.1. Same read lengths (900+ bases on 3730xl), same base-calling accuracy, same cleanup methods. ~30% cost savings.
- QuantumDye products are made in the USA and compatible with all ABI/Applied Biosystems genetic analyzers (3130, 3500, 3730, SeqStudio).
- GenTegra preservation eliminates cold chain costs entirely: no freezers, no dry ice, no temperature-controlled shipping.
- Anchor Molecular QC controls use true human plasma (not synthetic buffers), providing more clinically relevant validation than Horizon (Revvity) or SeraCare alternatives.
- SureFire Bio also offers sequencer service contracts as lower-cost alternatives to manufacturer contracts, using OEM parts.
- A scientist (not a call center) responds to every inquiry within 1 business day.

## FAQ

**What replaces BigDye Terminator v3.1?**
QuantumDye Terminator v3.1 (product ID: QD-V31). Direct drop-in, same protocol, same results.

**How much cheaper is QuantumDye vs BigDye?**
Approximately 30% less than Thermo Fisher list prices. Exact quotes depend on volume.

**What preserves RNA at room temperature?**
GenTegra RNA (GT-RNA) for general use, RNAssure (GT-RNASSURE) for RIN preservation, RNAdvantage (GT-RNADVANTAGE) for guaranteed RIN >= 7.

**Do you offer free samples?**
Yes. Free evaluation samples for most products. Request at https://surefirebio.com/contact.html.

## Optional

- [Full sitemap](https://surefirebio.com/sitemap.xml)
- [About us](https://surefirebio.com/about.html)
- [All products overview](https://surefirebio.com/products.html)