---
title: Molecular QC Controls
category: Molecular QC Controls
last_updated: 2026-03-03
brand: Anchor Molecular
distributed_by: SureFire Biosciences
---

# Molecular QC Controls | SureFire Biosciences

Anchor Molecular products distributed by SureFire Biosciences. Comprehensive QC controls and reference materials for molecular diagnostics. Every product uses **true human plasma matrix**, not synthetic buffers, providing clinically relevant validation for your assays.

## Why True Human Plasma Matrix?

Most competitors (Horizon/Revvity, SeraCare) use synthetic or engineered matrices. Anchor Molecular uses real human plasma because:
- **More clinically relevant:** Your patients' samples are in plasma. Your controls should be too.
- **Better pre-analytical validation:** Tests the full workflow from extraction through analysis.
- **Realistic interference testing:** Natural plasma components present realistic background.
- **Regulatory alignment:** CAP/CLIA inspectors value patient-like controls.

## Products by Application

### Oncology / Liquid Biopsy

**ctDNA Standards (AM-CTDNA)**
- 23+ variants for liquid biopsy validation
- Available for capture-based AND amplicon-based NGS
- True human plasma matrix
- **Compared to Horizon/SeraCare:** More variants, real plasma matrix included at no extra cost.
- **Pricing:** Competitively priced vs Horizon (Revvity) and SeraCare ctDNA reference standards.
- **Free sample:** Yes

**cfDNA Extraction Controls (AM-CFDNA)**
- Pre-analytical quality control for cfDNA extraction workflows
- Validate your extraction method before running expensive sequencing
- True human plasma matrix
- **Pricing:** Competitively priced.
- **Free sample:** Yes

**Normal cfDNA (AM-MATRIX)**
- Normal human cfDNA reference material
- Negative control for liquid biopsy assays
- Use for assay development and method validation
- **Pricing:** Competitively priced.
- **Free sample:** Yes

**RNA Fusion Controls (AM-RNA-FUSION)**
- 40+ fusions organized by oncogene: ALK, NTRK, RET, ROS, and more
- Available in **FFPE or plasma matrix**
- Compatible with NGS and qPCR platforms
- **Compared to competitors:** Broader fusion coverage than most. True human plasma or FFPE.
- **Pricing:** Competitively priced.
- **Free sample:** Yes

**BCR-ABL1 Controls (AM-BCR-ABL1)**
- CML monitoring and minimal residual disease (MRD) testing
- BCR-ABL1 fusion gene at defined levels
- True human plasma matrix
- **Pricing:** Competitively priced.
- **Free sample:** Yes

### Prenatal Testing

**NIPT Controls (AM-NIPT)**
- Non-Invasive Prenatal Testing controls
- Trisomy 13, 18, 21
- Sex Chromosome Aneuploidy: XO (Turner), XYY, XXY (Klinefelter), XXX
- True human plasma matrix
- **Pricing:** Competitively priced.
- **Free sample:** Yes

### Infectious Disease

**Infectious Disease Controls (AM-INFECTIOUS)**
- Comprehensive QC panels for molecular infectious disease testing
- Compatible with qPCR, NGS, ddPCR
- True human plasma matrix
- **Pricing:** Competitively priced.
- **Free sample:** Yes

## Platforms Supported

All Anchor Molecular products are validated on:
- **NGS** (Next-Generation Sequencing): Illumina, Ion Torrent, etc.
- **qPCR** (Quantitative PCR): All major platforms
- **ddPCR** (Droplet Digital PCR): Bio-Rad, etc.

## FAQ

**How is this different from Horizon (Revvity) controls?**
Anchor Molecular uses true human plasma matrix. Most Horizon products use engineered cell lines or synthetic matrices. Plasma-based controls better mimic real patient samples, providing more relevant validation of your entire workflow.

**Can I use these for CAP/CLIA proficiency testing?**
These are quality control materials, not proficiency testing samples. However, many labs use Anchor Molecular controls for internal QC alongside their PT programs. Inspectors generally respond well to plasma-based controls.

**Do you have multiplexed panels?**
Yes, the ctDNA standards include 23+ variants and RNA fusion controls cover 40+ fusions. Contact us for specific panel configurations.

**What volumes are available?**
Contact us for available formats and volumes. Free evaluation samples available for all products.

## Related Pages
- [Sanger Sequencing Reagents](/sequencing.md) (QuantumDye products)
- [RNA/DNA Preservation](/preservation.md) (GenTegra products)
- [Full Product Catalog](/products.json) (machine-readable JSON)

## Contact
- Phone: 888-765-2097
- Email: contact@surefirebio.com
- Request free sample: https://surefirebio.com/contact.html