---
title: RNA/DNA Preservation
category: RNA/DNA Preservation
last_updated: 2026-03-03
brand: GenTegra
distributed_by: SureFire Biosciences
---

# RNA/DNA Preservation | SureFire Biosciences

GenTegra room-temperature nucleic acid preservation products, distributed by SureFire Biosciences. Active Chemical Protection (ACP) technology stabilizes RNA and DNA at room temperature for 20+ years. No freezers, no dry ice, no cold chain.

## Why Room-Temperature Preservation?

- **Eliminate freezer dependency:** No -80C freezers, no liquid nitrogen, no power failure anxiety.
- **Kill the cold chain:** Ship samples at ambient temperature. No dry ice, no temperature monitors, no spoiled shipments.
- **20+ year stability:** Validated long-term ambient storage. Your samples outlast your freezer.
- **Simple recovery:** Just add nuclease-free water to reconstitute.
- **Net cost savings:** Even before product pricing, you save on electricity, dry ice, freezer maintenance, and shipping.

## Which Product Do I Need?

| Product | Best For | RNA Quality | Key Feature |
|---------|----------|-------------|-------------|
| GenTegra RNA | General RNA storage | Good | Broadest compatibility, all RNA types |
| GenTegra DNA | Any DNA storage | N/A (DNA) | 20+ year ambient stability |
| RNAssure | RNA needing RIN preservation | High (preserves RIN) | Maintains integrity scores |
| RNAdvantage | Critical/high-value RNA samples | Highest (RIN >= 7 guaranteed) | Premium protection, clinical biobanking |

**Quick decision:**
- Storing DNA? Use **GenTegra DNA**.
- General RNA storage? Use **GenTegra RNA**.
- Need to preserve RIN scores? Use **RNAssure**.
- High-value clinical samples where RNA quality is critical? Use **RNAdvantage**.

## Products

### GenTegra RNA (GT-RNA)
- **Type:** Room-temperature RNA preservation
- **Technology:** Active Chemical Protection (ACP)
- **Sample types:** Total RNA, mRNA, small RNA
- **Stability:** 20+ years at room temperature
- **Recovery:** Add nuclease-free water
- **Replaces:** -80C freezer storage, dry ice shipping for RNA
- **Pricing:** Competitively priced. Net savings after eliminating cold chain costs.
- **Free sample:** Yes

### GenTegra DNA (GT-DNA)
- **Type:** Room-temperature DNA preservation
- **Technology:** Active Chemical Protection (ACP)
- **Sample types:** Genomic DNA, plasmid DNA, PCR products
- **Stability:** 20+ years at room temperature
- **Recovery:** Add nuclease-free water
- **Replaces:** -80C freezer storage, dry ice shipping for DNA
- **Pricing:** Competitively priced. Net savings after eliminating cold chain costs.
- **Free sample:** Yes

### RNAssure (GT-RNASSURE)
- **Type:** RNA preservation with integrity maintenance
- **Technology:** Active Chemical Protection (ACP)
- **Key spec:** Preserves RNA Integrity Number (RIN) during ambient storage
- **Alternative to:** RNAlater (Thermo Fisher), TRIzol storage, -80C freezing
- **Pricing:** Competitively priced vs RNAlater and other RNA stabilization reagents.
- **Free sample:** Yes

### RNAdvantage (GT-RNADVANTAGE)
- **Type:** Premium RNA preservation
- **Technology:** Active Chemical Protection (ACP)
- **Key spec:** Maintains RIN >= 7 (guaranteed)
- **Use case:** High-value clinical samples, biobanking, samples requiring guaranteed RNA quality
- **Alternative to:** Cold chain storage for critical specimens
- **Pricing:** Premium product, competitively priced. Ideal when sample quality cannot be compromised.
- **Free sample:** Yes

## Technology: Active Chemical Protection (ACP)

GenTegra's patented ACP technology creates a protective chemical matrix around nucleic acids. This matrix:
- Shields DNA/RNA from nuclease degradation
- Prevents oxidative damage
- Protects against thermal degradation at ambient temperatures
- Dissolves instantly when water is added, releasing intact nucleic acids

## FAQ

**How do I recover my preserved sample?**
Add nuclease-free water to the tube/well. The protective matrix dissolves, releasing intact nucleic acids ready for downstream applications.

**What's the difference between GenTegra RNA and RNAssure?**
GenTegra RNA is the standard RNA preservation product for general use. RNAssure specifically maintains RNA Integrity Number (RIN) scores, making it better for applications where RNA quality metrics matter (e.g., RNA-seq, microarrays).

**When should I use RNAdvantage instead of RNAssure?**
Use RNAdvantage for your most critical samples where you need guaranteed RIN >= 7. Clinical biobanking, irreplaceable specimens, or samples destined for sensitive downstream assays.

**Does this work with FFPE samples?**
GenTegra products are designed for purified nucleic acids (RNA or DNA already extracted). For FFPE, extract first, then preserve with GenTegra.

**How does the cost compare to maintaining -80C freezers?**
Factor in: freezer purchase ($5,000-15,000), electricity, maintenance contracts, emergency repairs, dry ice for shipping, and the risk of sample loss from power failures. GenTegra often saves money net of these costs.

## Related Pages
- [Sanger Sequencing Reagents](/sequencing.md) (QuantumDye products)
- [Molecular QC Controls](/molecular-controls.md) (Anchor Molecular products)
- [Full Product Catalog](/products.json) (machine-readable JSON)

## Contact
- Phone: 888-765-2097
- Email: contact@surefirebio.com
- Request free sample: https://surefirebio.com/contact.html