Reference Standards You Can Trust
Our Anchor Molecular product line provides comprehensive QC controls and reference materials for oncology, infectious disease, prenatal testing, and more. Every product is designed to validate your assays with patient-like reference materials.
Oncology
ctDNA Standards
Multiplexed cell-derived variants in nucleosomal fragment format for liquid biopsy validation.
- 23+ multiplexed cell-derived variants (~150bp)
- Platform agnostic (capture-based) options
- 50+ variants in amplicon version (cell-derived + synthetic + fusions)
- 3% allele frequency, quantified by ddPCR
- Available in buffer or EDTA plasma matrix
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Extraction
cfDNA Extraction Controls
Comprehensive sensitivity and specificity panels for cell-free DNA extraction workflows.
- Sensitivity panels: 0%, 0.1%, 0.3%, 1%, 3% AF series
- Specificity controls for gDNA contamination monitoring
- gDNA concentration series (0 to 10 ng/ml)
- Patient-like reference material
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cfDNA
Normal Cell Free DNA
Wild-type cfDNA for negative controls and spiking experiments.
- Male cell line, Female (PAM3005), Pooled PBMC
- Available in TE buffer or pre-spiked in plasma
- Characterized and quantified
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Fusions
RNA Fusion Controls
Comprehensive fusion gene reference materials for oncology panel validation.
- 16 popular fusions by oncogene (ALK, NTRK, RET, ROS)
- 33+ fusions by cancer type (Lung, Sarcoma, Thyroid, etc.)
- Custom fusions available
- FFPE or plasma matrix options
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Hematology
BCR-ABL1 Control Panels
Standardized controls for CML monitoring across the international scale.
- e14a2, e13a2, e1a2 transcripts
- Compatible with Cepheid GeneXpert systems
- 10%IS (MR1.0) to 0.001%IS (MR5.0) range
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Biomarker
POLE-POLD1 Mutation Controls
FFPE-format controls for immunotherapy response prediction biomarkers.
- FFPE slices at 5% VAF
- POLE Exons 9, 11, 13, 14 + POLD1 Exon 12
- Relevant for immunotherapy eligibility testing
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Prenatal
NIPT Controls
Non-invasive prenatal testing controls for chromosome aneuploidy screening.
- Trisomy 13, 18 & 21 at 10% fetal fraction
- Sex Chromosome Aneuploidy (XO, XYY, XXY, XXX)
- For counting-based assays (e.g., Revvity Vanadis)
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Infectious Disease
Infectious Disease Controls
Comprehensive panel of non-pathogenic recombinant controls for molecular diagnostics.
- COVID-19/Influenza/RSV multiplex QC
- H5N1 (classic + Clade 2.3.4.4b)
- HIV-1, HBV, HCV controls
- Parainfluenza, Enterovirus D68, EEE
- Non-pathogenic, safe to handle
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Matrix
Matrix Products
Specialty matrices for assay development, spiking studies, and method validation.
- DNA-Depleted Plasma (for cfDNA spiking)
- RNA-Depleted Plasma (for cfRNA applications)
- Mass Spec Zero (delipidated, hormone-free serum)
- Immuno-Non-Reactive Serum
- HBV Negative Serum
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